Publications & COV


  • Benjamin Hubert, Muriel Marchi, Joseph Ly Vu, Camille Tranchant, Łukasz P. Tarkowski, Olivier Leprince and Julia Buitink1         2024     A method to determine antifungal activity in seed exudates by nephelometry Plant Methods vol 20 (1) p16
  • Thibault Barrit, Elisabeth Planchet, Jérémy Lothier, Pascale Satour, Sophie Aligon, Guillaume Tcherkez, Anis M. Limami, Claire Campion, Béatrice Teulat  . 2024. Nitrogen Nutrition Modulates the Response to Alternaria brassicicola Infection via Metabolic Modifications in Arabidopsis Seedlings. Plants. 13 (4), pp.534


  • Mailen Ortega-Cuadros , Sophie Aligon, Nubia Velasquez, Jerome Verdier, Philippe Grappin. 2023.  Arabidopsis transcriptome dataset of the response of imbibed wild-type and glucosinolate-deficient seeds to nitrogen-containing compounds Data in brief. 48:109047
  • Thomas Charpentier, Guillaume Viault, Anne-Marie Le Ray, Nelly Bataillé-Simoneau, Jean-Jacques Helesbeux, Nadège Blon, Franck Bastide, Muriel Marchi, Sophie Aligon, Antoine Bruguière, Chau Phi Dinh, Zahia Benbelkacem, Jean-Felix Dallery, Philippe Simoneau, Pascal Richomme and Thomas Guillemette. 2023. Natural Products Targeting the Fungal Unfolded Protein Responseas an Alternative Crop Protection Strategy. Journal of Agricultural and Food Chemistry. 71 (37), 13706-13716
  • Nabahat Bessadat, Bruno Hamon, Nelly Bataillé-Simoneau, Nisserine Hamini-Kadar, Mabrouk Kihal, Philippe Simoneau.  2023. Identification and characterization of fungi associated with leaf spot/blight and melting-out of turfgrass in Algeria. Phytopathologia Mediterranea. 62 (1), pp.73-93


  • Courtial J., Jean-Jacques Helesbeux, Hugo Oudart, Sophie Aligon, Muriel Bahut,Bruno Hamon, Guillaume N’Guyen, Sandrine Pigné, Ahmed G. Hussain, Claire Pascouau, Nelly Bataillé-Simoneau, Jérôme Collemare, Romain Berruyer, Pascal Poupard.2022. Characterization of NRPS and PKS genes involved in the biosynthesis of SMs in the phytopathogenic fungus Alternaria dauci, including the phytotoxic polyketide aldaulactone. Scientific Reports. 12: 8155
  • Bessadat, N., Hamon, B., Bataillé-Simoneau, N., Colou, J., Mabrouk, K., Simoneau, P. 2022. Characterization of Stemphylium spp. associated with tomato foliar diseases in Algeria. Phytopathologia Mediterranea. 61(1): 39-53.
  • Bréard D., Thibault Barrit, Daniel Sochard, Sophie Aligon, Elisabeth Planchet, Béatrice Teulat, Josiane Le Corff, Claire Campion, David Guilet. 2022. Development of a quantification method for routine analysis of glucosinolates and camalexin in brassicaceous small-sized samples by simultaneous extraction prior to liquid chromatography determination. Journal of chromatography B    .1205 : 123348
  • Kwasiborski A., Bastide F., Hamon B., Poupard P., Simoneau P., Guillemette T. 2022. In silico analysis of RNA interference components and miRNAs-like RNAs in the seed-borne necrotrophic fungus Alternaria brassicicola. Fungal Biology 126:224-234
  • Guillou Marie-Charlotte, Emilie Vergne, Sophie Aligon, Sandra Pelletier, Fabienne Simonneau, Aurélia Rolland, Salem Chabout, Gregory Mouille, , Kay Gully, Philippe Grappin, Françoise Montrichard, Sébastien Aubourg, and Jean-Pierre Renou. 2022. The peptide SCOOP12 acts on reactive oxygen specieshomeostasis to modulate cell division and elongation in Arabidopsis primary root. Journal of Experimental Botany. 73(18), 6115–6132
  • Ortega-Cuadros Mailen, Laurine Chir, Sophie Aligon, Tatiana Arias, Jerome Verdier, Philippe Grappin. 2022. Dual-transcriptomic datasets evaluating the effect of the necrotrophic fungus Alternaria brassicicola on Arabidopsis germinating seeds. Data in Brief . 44,108530
  • Ortega-Cuadros Mailen, Tiago Lodi De Souza, Romain Berruyer, Sophie Aligon, Sandra Pelletier, Jean-Pierre Renou, Tatiana Arias, Claire Campion, Thomas Guillemette, Jérome Verdier and Philippe Grappin. 2022. Seed Transmission of Pathogens: Non-Canonical ImmuneResponse in Arabidopsis Germinating Seeds Compared to Early Seedlings against the Necrotrophic FungusAlternaria brassicicola. Plants. 11 (13) : 1708
  • Barakat I., Chtaina N., El Kamli T., Grappin P., El Guilli M., Ezzahiri B.    2022     Bioactivity of Trichoderma harzianum A peptaibols against Zymoseptoria tritici causal agent of septoria leaf blotch of wheat. Journal of Plant Protection research 63 (1), pp.59-67
  •  Z. Jiang, M. Wang, M. Nicolas, L. Ogé, M.D. Pérez-Garcia, L. Crespel, G. Li, Y. Ding, J. Le Gourrierec, P. Grappin, and S. Sakr. 2022. Glucose-6-Phosphate dehydrogenases: the hidden players of plant physiology. International Journal of Molecular Sciences, 2022, 23 (24), pp.16128.
  • Thibault Barrit, Claire Campion, Sophie Aligon, Julie Bourbeillon, David Rousseau, Elisabeth Planchet and Béatrice Teulat. 2022. A new in vitro monitoring system reveals a specific influence of Arabidopsis nitrogen nutrition on its susceptibility to Alternaria brassicicola at the seedling stage. Plant Methods. 18 : 131
  • Pascouau C., C. Chateau, F. Bastide, T. Le Moullec-Rieu, T. Guillemette, B. Hamon, S. ALigon, A. Cailleau, D. Sochard, J. Gombert, E. Morel, E. Laurent, I. Sérandat, R. Berruyer, P. Poupard. 2022. Characterization and pathogenicity of Fusarium spp. isolates causing root and collar rot on carrot. Canadian Journal of Plant Pathology . 45 (1), 76-91.


  • Bessadat, N., Hamon, B., Bataillé-Simoneau, N., Mabrouk, K., Simoneau, P. 2021 Characterization of New Small-Spored Alternaria Species Isolated from Solanaceae in Algeria. Life, 11, 1291
  • N'Guyen G., R. Raulo, A. Porquier, M. Marchi, B. Iacomi, S. Pelletier, J.-P. Renou, N. Bataillé-Simoneau, C. Campion, B. Hamon, A. Kwasiborski, P. Hudhomme, D. Macherel, P. Simoneau,T. Guillemette. 2021. Responses of the necrotrophic fungus Alternaria brassisicola to the indolic phytoalexin brassinin. Frontiers in Plant Science 11:2216
  • Merieux N., P. Cordier, M‑H. Wagner, S. Ducournau, S. Aligon, D. Job, P. Grappin, E. Grappin. 2021. ScreenSeed as a novel high throughput seed germination phenotyping method. Scientific Reports. 11:1404
  • van Bohemen A.I., Nicolas Ruiz, Aurore Zalouk-Vergnoux, Aurore Michaud, Thibaut Robiou du Pont, Irina Druzhinina, Lea Atanasova, Soizic Prado, Bernard Bodo, Laurence Meslet-Cladiere, Bastien Cochereau, Franck Bastide, Corentin Maslard, Muriel Marchi, Thomas Guillemette, and Yves François Pouchus.2021. Pentadecaibins I–V: 15-Residue Peptaibols Produced by a Marine-Derived Trichoderma sp. of the Harzianum Clade. Journal of Natural Products. 84, 4, 1271–1282
  • Hammad, M., Guillemette, T., Alem, M., Bastide, F., Louanchi, M. 2021. First report of three species of Trichoderma isolated from the rhizosphere in Algeria and the high antagonistic effect of Trichoderma brevicompactum to control grey mould disease of tomato.Egyptian Journal of Biological Pest Control. 31:85


  • Leyte-Lugo M., P. Richomme, P.  Poupard, L. M. Peña-Rodriguez 2020.Identification and Quantification of a Phytotoxic Metabolite from Alternaria dauci.Molecules. 25:4003
  • Barakat I, Chtaina N, Grappin P, El Guilli M, Abdenbi E, Ezzahiri B.2020.Efficacy of Secondary Metabolites Produced by Bacillus Amyloliquefaciens on the Inhibition of Zymoseptoria TriticiGlobal Journal of Science Frontier Research/ D Agriculture and Veterinary. 20: 9-16
  • Bessadat N, Hamon B, Bataillé-Simoneau N, Chateau C, Mabrouk K, Simoneau P. 2020. Occurrence of Leaf Spot Disease Caused by Alternaria crassa (Sacc.) Rands on Jimson Weed and Potential Additional Host Plants in Algeria. Plant Pathology Journal. 36(2): 1-6
  • Bessadat N, Hamon B, Bataillé-Simoneau N, Mabrouk K, Simoneau P. 2020. Alternaria telliensis sp. nov., a new species isolated from Solanaceae in Algeria. Phytotaxa. [In press]


  • Ayad D, Aribi D, Hamon B, Kedad A, Simoneau P, Bouznad Z. 2019 Distribution of large-spored Alternaria species associated with early blight of potato and tomato in Algeria Phytopathologia Mediterranea 58(1): 139-149
  • Gully K,  Pelletier S, Guillou MC, Ferrand M, Aligon S, Pokotylo I,  Perrin A, Vergne E, Fagard M, Ruelland E, Grappin P, Bucher E, Renou JP, Aubourg S. 2019. The SCOOP 12 peptide regulates defense response and root development in Arabidopsis thaliana. Journal of experimental botany 70(4):1349-1365
  • Bessadat N., Hamon B., Bataillé-Simoneau N., Mabrouk K.,  Simoneau P. 2019. First Report of Alternaria dauci Causing Leaf Blight of Coriander (Coriandrum sativum) in Algeria. Plant disease. 103(9):2471
  • Barakat I, Chtaina N, Grappin P, El Guilli M, Ezzahiri B, Aligon S, Neveu M, Marchi M 2019 Induced Systemic Resistance (ISR) in Arabidopsis thaliana by Bacillus amyloliquefaciens and Trichoderma harzianum used as seed treatments Agriculture 9(8):166
  • N'Guyen G, R Raulo, M Marchi, C Agusti Brisach, B Iacomi, S Pelletier, JP Renou, N Bataillé-Simoneau, C Campion, F Bastide, B Hamon, C Mouchès, B Porcheron, R Lemoine, A Kwasiborski, P Simoneau, T Guillemette 2019 Responses to hydric stress in the seed-borne necrotrophic fungus Alternaria brassicicola Frontiers in Microbiology-Plant Microbe Interactions 10:1-16 (article 1969)
  • Le Moullec-Rieu T, C. Chateau, C. Pascouau, F. Bastide, B. Hamon, P. Poupard, E. Laurent, J. Gombert, E.Morel, I. Sérandat,  P.L. Guillermin, P.E. Brandeis, S. Mallard 2019 First Report of Root and Collar Rot Caused by Fusarium tricinctum and Fusarium avenaceum on Carrot in France .Plant Disease 104(2) : 591
  • Colou J, GQ N’Guyen, O Dubreu, K Fontaine, A Kwasiborski, F Bastide, F Manero, B Hamon, S Aligon, P Simoneau, T Guillemette 2019 Role of Membrane Compartment Occupied by Can1 (MCC) and eisosome subdomains in plant pathogenicity of the necrotrophic fungus Alternaria brassicicolaBMC Microbiology 19, 295
  • Wang M., Oge L., Voisine L., Perrez-Garcia M. D., Jeauffre, J., Hibrand Saint-Oyant, L., Grappin P., Hamama L., Sakr, S 2019 Posttranscriptional regulation of RhBRC1 (Rosa hybrida BRANCHED1) in response to sugars is mediated via its own 3′ untranslated region,with a potential role of RhPUF4 (Pumilio RNA-Binding Protein Family) International Journal of Molecular Science 20 (15), 3808


  • Pateau V, Razafimandimby B, Vandeputte P, Thornton CR, Guillemette T, Bouchara JP, Giraud S. 2018. Gene Disruption in Scedosporium aurantiacum: Proof of Concept with the Disruption of SODC Gene Encoding a Cytosolic Cu,Zn-Superoxide Dismutase.
  • Rezki S, Campion C, Simoneau P, Jacques M-A, Shade A, Barret M. 2018. Assembly of seed-associated microbial communities within and across successive plant generations. Plant & Soil . 10.1007/s11104-017-3451-2
  • Belmas E, Briand M, Kwasiborski A, Colou J, N'Guyen G, Iacomi B, Grappin P, Campion C, Simoneau P, Barret M, Guillemette T. 2018. Genome sequence of the necrotrophic plant pathogen Alternaria brassicicola Abra43. Genome Announcements.6(6):e01559-17
  • E B. Nelson,  P. Simoneau,  M. Barret,  B. Mitter, S. Compant. 2018. Editorial special issue: the soil, the seed, the microbes and the plant. Plant & Soil. 422:1–5
  • Courtial J., L. Hamama, J-J. Helesbeux, M. Lecomte, Y. Renaux, E. Guichard, L. Voisine, C. Yovanopoulos, B. Hamon, L. Ogé, P. Richomme, M. Briard, T. Boureau, S.  Gagné, P. Poupard and R. Berruyer. 2018.Aldaulactone – a newly described phytotoxic secondary metabolite involved in the aggressiveness of Alternaria dauci on carrot. Frontiers in Plant Science . 9:502. doi: 10.3389/fpls.2018.00502
  • Ayad D, Hamon B, Kedad A, Bouznad Z, Simoneau P.2018.First report of early blight caused by Alternaria linariae on potato in Algeria. Plant Disease. 102(12):2651
  • Warneys, R., Gaucher, M., Robert, P., Aligon, S., Anton, S., Aubourg, S., Barthes, N., Braud, F., Cournol R., Gadenne, C., Heintz, C., Brisset, M.-N., Degrave, A. 2018. Acibenzolar-S-Methyl Reprograms Apple TranscriptomeToward Resistance to Rosy Apple Aphid. Frontiers in Plant Science. 9:1-16


  • Pigné S, Zykwinska A, Janod E, Cuenot S, Kerkoud M, Raulo R, Bataillé-Simoneau N, Marchi M, Kwasiborski A, N’Guyen G, Mabilleau G, Simoneau P, Guillemette T . 2017 .  A flavoprotein supports cell wall properties in the necrotrophic fungus Alternaria brassicicola. Fungal Biology and Biotechnology   4:1-13
  • Bastide F., I. Sérandat, J. Gombert, E. Laurent, E. Morel, J. Kolopp, P.L. Guillermin, B. Hamon, P. Simoneau, R. Berruyer, P. Poupard . 2017. Characterization of fungal pathogens (Diaporthe angelicae and D. eres) responsible for umbel browning and stem necrosis on carrot in France. Plant Pathology 66: 239-253
  • Bessadat N.,  Berruyer R., Hamon B., Bataillé-Simoneau N., Benichou S., Kihal M., Henni D.E., Simoneau P.  2017    Alternaria species associated with early blight epidemics on tomato and other Solanaceae crops in northwestern Algeria. Eur. J. Plant Pathol. : 148:181-197
  • Ayad D, Leclerc S, Hamon B, Kedad A, Bouznad Z, Simoneau P     2017    First report of early blight caused by Alternaria protenta on potato in Algeria. Plant Disease 101(5): 836


  • Rezki S, Campion C, Iacomi-Vasilescu B, Préveaux A, Toualbia Y, Bonneau S, Briand M, Laurent E, Hunault G, Simoneau P, Jacques MA, Barret M. 2016. Differences in stability of seed-associated microbial assemblages in response to invasion by phytopathogenic microorganisms.  PeerJ   4:e192
  • Bessadat N, Hamon B, Henni D.E., Simoneau P. 2016. First report of tomato early blight caused by Alternaria grandis in Algeria.Plant Disease.100(2): 533
  • Le Clerc  V., Auperpin E., Suel A., Rousseau D., Belin E., Poupard P., Lambert J.,Voisine L., Hamama L., Boureau T., Berruyer R., Barrot L., Prieur R., Briard M.  2016. Etude de la résistance partielle de la carotte à Alternaria dauci par une approche de phénotypage multicritères.  Innovations Agronomiques.  50:101-109


  • Le Clerc V., Suel A., Pawelec A., Marques S., Huet S., Lecomte M., Poupard P., Briard M. 2015. Is there variety x isolate interaction in the polygenic quantitative reistance of carrot to Alternaria dauci? Euphytica. 202:235-243
  • Barret M, Briand M, Bonneau S, Préveaux A, Valière S, Bouchez O, Hunault G, Simoneau P, Jacques MA. 2015. Emergence shapes the structure of the seed-microbiota. Appl. Environ. Microbiol.81:1257-1266
  • Rousseau C., Hunault G., Gaillard S., Bourbeillon J., Montiel G., Simier P., Campion C., Jacques M. A., Belin E., Boureau T.2015. Phenoplant : a web resource for the exploration of large chlorophyll fluorescence image datasets. Plant Methods, 11:24:00
  • Calmes B., N'Guyen G., Dumur J., Agusti-Brisach C., Campion C, Iacomi B, Pigné S.,Dias E., Macherel D., Guillemette T., Simoneau P. 2015. Glucosinolate-derived isothiocyanates impact mitochondrial function in fungal cells and elicit an oxidative stress response necessary for growth recovery. Frontiers in Plant Science. 6:414 doi: 10.3389/fpls.2015.00414
  • Calmes B., Morel-Rouhier M., Bataillé-Simoneau N., Gelhaye E., Guillemette T., Simoneau P. 2015. Characterization of Alternaria brassicicola Glutathione transferases involved in protection against Brassicaceae defenses metabolites. BMC Microbiology. 15:123
  • Bessadat N, Hamon B, Henni D.E., Simoneau P. 2015. First report of tomato early blight caused by Alternaria grandis in Algeria. Plant Press


  • Ménard L.,P.E.  Brandeis, P. Simoneau, P. Poupard, I. Sérandat, J. Detoc, L. Robbes, F. Bastide, E. Laurent, J. Gombert, E. Morel 2013 .First report of Umbel Browning and Stem Necrosis caused by Diaporthe angelicae on carrot in France.Plant Disease,98 (3):421-422
  • Guillemette T., B. Calmes, P. Simoneau. 2014.Impact of the UPR on the virulence of the plant fungal pathogen A. brassicicola. Virulence, 5:2, 1–8
  • Davanture M., J. Dumur, N. Batailé-Simoneau, C. Campion, B. Valot, M. Zivy, P. Simoneau, S. Fillinger. 2014. Phosphoproteome profiles of the phytopathogenic fungi Alternaria brassicicola and Botrytis cinerea during exponential growth in axenic cultures. Proteomics, 14:1639-1645
  • Zykwinska A, Guillemette T., Bouchara J.P., Cuenot S. 2014. Spontaneous self-assembly of SC3 hydrophobins into nanorods in aqueous solution. Biochimica et Biophysica Acta. 1844 : 1231–1237
  •  Lecomte M., L. Hamama, L. Voisine, J. Gatto, J.J. Hélesbeux, D. Séraphin, L.M. Peña-Rodriguez, P. Richomme, C. Boedo, C. Yovanopoulos, M. Gyomlai, M. Briard, P. Simoneau, P. Poupard, et R. Berruyer. 2014. Partial resistance of carrot to Alternaria dauci correlates with in vitro cultured carrot cell resistance to fungal exudates. Plos One, 9(7):e101008 doi:10.1371/journal.pone.0101008
  • Bessadat N ,Simoneau P, Benichou S, Setti B, Kihal M,  Henni D. 2014. Morphological, physiological and pathogenic variability of small-spore Alternaria sp. causing leaf blight of Solanaceous plants in Algeria. Afr. J. Microbiol. Res., 8(37):3422-3434


  • Calmes B, Guillemette T, Teyssier L, Siegler B, Pigné S, Landreau A, Iacomi B, Lemoine R, Richomme P, Simoneau P. 2013. Role of mannitol metabolism in the pathogenicity of the necrotrophic fungus Alternaria brassicicola. Frontiers in Plant Science, 4:131. doi: 10.3389/fpls.2013.00131
  • Gaucher M, Dugé de Bernonville T, Lohou D, Guyot S, Guillemette T, Brisset MN, Dat JF. 2013. Histolocalisation and physicol-chemical characterization of dihydrochalcones: insight into the role of apple major flavonoids. Phytochemistry, 90:78-89
  • Pochon S, Simoneau P, Pigné S, Balidas S, Bataillé-Simoneau N, Campion C, Jaspard E, Calmes B, Hamon B, Berruyer R, Juchaux M, Guillemette T. 2013. Dehydrin-like proteins in the necrotrophic fungus Alternaria brassicicola have a role in plant pathogenesis and stress response. Plos One, 8(10): e75143. doi:10.1371/journal.pone.0075143


  • Boedo C., S. Bénichou, R. Berruyer, S. Bersihand, A. Dongo., P. Simoneau,M. Lecomte, M.  Briard, V. Le Clerc, et P. Poupard. 2012. Evaluating  aggressiveness and host range of Alternaria dauci in a controlled environment. Plant Pathology, 61: 63-75.
  • Lecomte M., Berruyer R., Hamama L., Boedo C., Hudhomme P., Bersihand S., Arul J., N’Guyen G., Gatto J., Guilet D., Richomme P., Simoneau P., Briard M., Le Clerc V., et Poupard P. 2012. Inhibitory effects of the carrot metabolites 6-methoxymellein and falcarindiol on development of the fungal leaf blight pathogen Alternaria dauci. Physiological and Molecular Plant Pa, 80:58-67
  • Pochon S., E. Terrasson,T.  Guillemette., B.  Iacomi-Vasilescu, S. Georgeault, M. Juchaux, R. Berruyer, I. Debeaujon, P. Simoneau, et C. Campion. 2012. The Arabidopsis thaliana-Alternaria brassicicola pathosystem: a model interaction for investigating seed transmission of necrotrophic fungi. Plant Methods, 8: 16-29


  • Simoneau P, Guillemette T, Richomme P, Helesbeux JJ (2012) Potentiating agents for protecting plants from fungal infections. European patent EP 12 176 613.3


  • JOUBERT A., SIMONEAU P., CAMPION C., BATAILLE-SIMONEAU N., IACOMI-VASILESCU B., POUPARD P., FRANCOIS J.M., GEORGEAULT S., SELLIER E., GUILLEMETTE T. (2011) Impact of the unfolded protein response on the pathogenicity of the necrotrophic fungus Alternaria brassicicola. Molecular Microbiology 79, 1305-24.
  • JOUBERT A., BATAILLE-SIMONEAU N., CAMPION C., GUILLEMETTE T., HUDHOMME P., IACOMI-VASILESCU B., LEROY T., POCHON S. POUPARD P., SIMONEAU P., (2011) Cell wall integrity and high osmolarity glycerol pathways are required for adaptation of Alternaria brassicicola to cell wall stress caused by brassicaceous indolic phytoalexins. Cellular Microbiology 13, 62-80.
  • GUILLEMETTE T., RAM A. F. J., CARVALHO N.D.S.P., JOUBERT A., SIMONEAU P., ARCHER D. (2011). Methods for investigating the UPR in filamentous fungi. Methods in Enzymology 490, 1-29.


  • BOEDO C., BERRUYER R., LECOMTE M., BERSIHAND S., BRIARD M., LE CLERC V., SIMONEAU P., POUPARD P., (2010) Evaluation of different methods for the characterization of carrot resistance to the Alternaria leaf blight pathogen (Alternaria dauci) revealed two qualitatively different resistances. Plant Pathology 59, 368-375.
  • JOUBERT A., CALMES B., BERRUYER R., PIHET M., BOUCHARA J.P., SIMONEAU P., GUILLEMETTE T., (2010). Laser nephelometry applied in an automated microplate system to study filamentous fungus growth. BioTechniques 48 (5), 399-404.

Date de modification : 09 avril 2024 | Date de création : 11 mai 2011 | Rédaction : NBS